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Index > Protein center > Ctsb(Gene name) > Mouse
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  • Ctsb (Gene name),
  • Cathepsin B (Protein name ),  CATB_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ctsb;
    Protein name:
    Cathepsin B;
    Alternative:
    Cathepsin B1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with SRPX2 (By similarity). Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.
    Function:
    Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
    Subcellular Location:
    Lysosome Melanosome
    Protein Attributes:
    Sequence length:
    339
    Sequence:
    50:
    MWWSLILLSC | LLALTSAHDK | PSFHPLSDDL | INYINKQNTT | WQAGRNFYNV | 
    100:
    DISYLKKLCG | TVLGGPKLPG | RVAFGEDIDL | PETFDAREQW | SNCPTIGQIR | 
    150:
    DQGSCGSCWA | FGAVEAISDR | TCIHTNGRVN | VEVSAEDLLT | CCGIQCGDGC | 
    200:
    NGGYPSGAWS | FWTKKGLVSG | GVYNSHVGCL | PYTIPPCEHH | VNGSRPPCTG | 
    250:
    EGDTPRCNKS | CEAGYSPSYK | EDKHFGYTSY | SVSNSVKEIM | AEIYKNGPVE | 
    300:
    GAFTVFSDFL | TYKSGVYKHE | AGDMMGGHAI | RILGWGVENG | VPYWLAANSW | 
    339:
    NLDWGDNGFF | KILRGENHCG | IESEIVAGIP | RTDQYWGRF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cathepsin B
    Cat.:
    E0405m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Cathepsin B
    Cat.:
    E0405r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Cathepsin B
    Cat.:
    E0405b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Cathepsin B
    Cat.:
    E0405h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Cathepsin B
    Cat.:
    E0405p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Cathepsin B
    Cat.:
    E0405c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cathepsin B
    Cat.:
    U0405r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cathepsin B
    Cat.:
    U0405c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cathepsin B
    Cat.:
    U0405b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cathepsin B
    Cat.:
    U0405p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cathepsin B
    Cat.:
    U0405h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Cathepsin B
    Cat.:
    U0405m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Cathepsin B
    Polyclonal Antibody for Mouse Cathepsin B
    Cat.:
    P0405Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cathepsin B
    Cat.:
    P0405Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cathepsin B
    Cat.:
    P0405Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cathepsin B
    Polyclonal Antibody for Mouse Cathepsin B
    Monoclonal Antibody for Mouse Cathepsin B
    Monoclonal Antibody for Mouse Cathepsin B
    Monoclonal Antibody for Mouse Cathepsin B
    Monoclonal Antibody for Mouse Cathepsin B
    Monoclonal Antibody for Mouse Cathepsin B
    Monoclonal Antibody for Mouse Cathepsin B
    Protein for Mouse Cathepsin B
    Protein for Mouse Cathepsin B
    Protein for Mouse Cathepsin B
    Protein for Mouse Cathepsin B
    Protein for Mouse Cathepsin B
    Protein for Mouse Cathepsin B

    R&D Technical Data
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           12% SDS-PAGE Analysis

     

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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤ 5.2%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤ 8.3%

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    Recovery
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    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    97

    92-105

    Plasma

    96

    93-104

     

     

     

     

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    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    88-101%

    90-103%

    93-105%

    92-102%

    EDTA plasma(n=5)

    89-99%

    93-101%

    89-98%

    90-105%

    heparin plasma(n=5)

    92-101%

     

    94-105%

    98-107%

    95-108%

     

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    References
    1. 1.
      "The structure of the mouse cathepsin B gene and its putative promoter."
      Qian F. , Frankfater A. , Chan S.J. , Steiner D.F.
      DNA Cell Biol.10:159-168(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
    3. 3.
      "Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs."
      Chan S.J. , San Segundo B. , McCormick M.B. , Steiner D.F.
      Proc. Natl. Acad. Sci. U.S.A.83:7721-7725(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Characterization of multiple cathepsin B mRNAs in murine B16a melanoma."
      Qian F. , Frankfater A. , Steiner D.F. , Bajkowski A.S. , Chan S.J.
      Anticancer Res.11:1445-1451(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
    5. 5.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Placenta.
      tissue: Thymus.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary gland.
    7. 7.
      "Isolation of a cathepsin B-encoding cDNA from murine osteogenic cells."
      Friemert C. , Closs E.I. , Silbermann M. , Erfle V. , Strauss P.G.
      Gene103:259-261(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 314-339
    8. 8.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-220;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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